Tiffany McLamarrah, PhD, and colleagues publish new study on the regulation of centriole duplication. Centriole duplication is tightly regulated throughout the cell cycle to ensure one duplication event per centriole. McLamarrah et al. show that a stepwise pattern of Ana2 phosphorylation by Plk4 facilitates proper centriole duplication providing molecular insight into the assembly process of this organelle.
