News
Darren Cusanovich, PhD, led a study published in the most recent issue of Cell presenting a single-cell atlas of chromatin (how the genome is packaged in the nucleus of a cell) patterns in adult mice based on data from almost 100,000 individual cells. Their work sheds light on how the various cell types present in mammals are able to accomplish such different functions while referencing the same genome. This resource may ultimately help us to understand precisely how human diseases develop and manifest in complex tissues.
Marco Padilla-Rodriguez, PhD – a recent CMM graduate from Dr. Gus Mouneimne’s lab- and colleagues have recently published a new study in Nature Communications highlighting estrogen’s dual effects of promoting tumor growth in estrogen receptor-positive (ER+) breast cancer, and suppressing tumor invasion through actin cytoskeletal remodeling.
Congratulations to Diana Darnell, PhD for her promotion to full Professor, Educator Scholar Track!
Lifelong cytomegalovirus infection may be beneficial, boosting the immune system in old age, when we need it most, according to a study led by University of Arizona researchers published in the Proceedings of the National Academy of Sciences.
University of Arizona physicians and researchers remember Dr. Bowden as a “friend, mentor, passionate scientist and remarkable human being.”
The three-year Arizona Biomedical Research Commission Awards will fund research relating to neuropathic and cancer pain, migraines, opioids, antibiotics, antivirals, sinusitis, obesity, diabetes, Parkinson’s disease, pulmonary disease and pediatric acute-onset neuropsychiatric syndrome.
Megha Padi, PhD, harnesses the computational power of bioinformatics to learn more about cancer and how best to treat it — and empowers other cancer researchers to do the same.
Curtis Thorne, PhD, and colleagues published a new study in Developmental Cell describing a simple, scalable method to culture 2D enteroid monolayers that, surprisingly, recapitulates many of the features of in vivo intestinal tissue and can be used for high-throughput microscopy-based experiments. Using this system, they systematically perturb WNT and BMP signals to reveal a core morphogenic circuit that controls proliferation, tissue organization, and cell fate or the intestine.
CMM is delighted to welcome the following new PhD students who are entering the Graduate Program in Molecular Medicine: Alice Solomon, (Romanoski Lab), Austin Conklin (Romanoski Lab) and Rhye-Samuel Kanassatega (Colson Lab). We also extend a friendly welcome to the following Cancer Biology PhD students who will be working in labs with CMM faculty: Carly Cabel (Thorne Lab), Corbin Jensen (Warfel Lab) and Shekha Tahsin (Miranti Lab).
An inspiration from THE DESERT – two team-building murals by CMM Faculty and Family. We had a blast at Creative Juice Bar on Tuesday evening (3/6/2018)!